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MSK2, active, GST tagged from mouse

品牌
Sigma-Aldrich
货号
SRP5222
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6468.88 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
MSK2, active, GST tagged from mouse
RSKB
RSK-B
RPS6KA4
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

MSK2 (mitogen- and stress-activated protein kinase-2) is a member of the serine/threonine kinase family that contains two non-identical kinase catalytic domains. MSK2 is also known as ribosomal protein S6 kinase polypeptide 4 (RPS6KA4), that is activated by the mitogen-activated protein kinases- extracellular signal-regulated kinases 1 and 2 (ERK1 and -2) and p38.

生化/生理作用

MSK2 (mitogen- and stress-activated protein kinase-2) phosphorylates various substrates like cyclic AMP-responsive element-binding protein 1 (CREB1) and the proto-oncogene c-fos. It is a histone-modifying enzyme and a mitogenic factor. The protein is involved in the G1-phase of the cell cycle and has a role in apoptosis. It also modulates the functions of various transcription factors.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 7.5-10.4 nmol/min·mg
分子量 ~114 kDa
NCBI登记号 BC012964
运输 dry ice
储存温度 ?70℃
Gene Information mouse ... Rps6ka4(56613)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1

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