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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-WISP2 antibody produced in mouse

Monoclonal Anti-WISP2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1401444
规格纯度
clone 1E11, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-WISP2 antibody produced in mouse
CTGF-L
CCN5
CT58
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. (provided by RefSeq)

免疫原

WISP2 (AAH17782.1, 24 a.a. ~ 250 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDCSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSPQNSAF

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 1E11, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) capture ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2aκ
NCBI登记号 BC017782
UniProt登记号 O76076
运输 dry ice
储存温度 ?20℃
Gene Information human ... WISP2(8839)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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