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Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat

品牌
Sigma-Aldrich
货号
SAB4200684
规格纯度
clone DECMA-1, purified from hybridoma cell culture
价格
6732.28 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat
LCAM
CDHE
cadherin 1
type 1
CD324
E-cadherin (epithelial)
Arc-1
ECAD
UVO
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Monoclonal Anti-Uvomorulin/E-Cadherin (rat IgG1 isotype) is derived from the DECMA-1 hybridoma produced by the fusion of rat myeloma cells and splenocytes from an immunized Lou rat. Uvomorulin/E-Cadherin (Epithelial cadherin), also known as CDH1, CAM 120/80, L-CAM (Cell-Adhesion Molecule) or CD324, is a member of the cadherin transmembrane glycoproteins superfamily. It is characterized with a highly conserved cytoplasmic tail.

免疫原

Mouse embryonal carcinoma cell line PCC4 Aza RI

应用

Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat has been used in various immunochemical techniques including immunoblotting, immunoprecipitation, immunohistochemical staining and immunofluorescent staining.

生化/生理作用

E-cadherin is a calcium-dependent glycoprotein. It is responsible for the homogeneous attachment between cells. It suppresses malignant transformation of tumors. Additionally, it also regulates cellular invasion and metastasis.
Cadherins contribute to epithelial cell behavior and tissue morphogenesis/remodeling by facilitating cell-cell adhesion. Monoclonal Anti-Uvomorulin/E-Cadherin can be used for studies of embryonal development, cell-cell interaction of cells grown in culture, and localization of E-Cadherin. In addition, it is commonly used as an E-cadherin inhibitor/blocking antibody in a study of embryonic stem cells (EMS).

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 rat
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 DECMA-1, monoclonal
形式 buffered aqueous solution
分子量 antigen ~120 kDa
species reactivity dog, mouse
浓度 ~1 mg/mL
technique(s) immunoblotting: 0.5-1 μg/mL using whole extract of MDCK cells.
immunofluorescence: 5-10 μg/mL using MDCK cells
immunoprecipitation (IP): suitable
同位素/亚型 IgG1
运输 dry ice
储存温度 ?20℃

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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