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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-TNRC6C antibody produced in mouse

Monoclonal Anti-TNRC6C antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403333
规格纯度
clone 3G11, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-TNRC6C antibody produced in mouse
FLJ20015
KIAA1582
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Mouse monoclonal antibody raised against a partial recombinant TNRC6C.
TNRC6C (Trinucleotide repeat containing 6C) is a member of GW182 (Gly-Trp) family consisting of a domain similar to Drosophila GW182 (also known as Gawky), a domain rich in GW or WG repeats followed by a glutamine (Q)-rich region at the N-proximal end, a central ubiquitin-associated (UBA) domain and an RNA-binding domain termed as RRM.

免疫原

TNRC6C (NP_061869, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAK

应用

Monoclonal Anti-TNRC6C antibody produced mouse is suitable for indirect ELISA.

生化/生理作用

TNRC6C (Trinucleotide repeat containing 6C) plays an important role in the microRNA repression during protein synthesis via miRNA pathway. The C-terminal RRM RNA-binding domain mediates the process of translational repression. Its GW-rich and Q-rich domain also suppress the expression for protein synthesis by binding to a reporter mRNA. In addition to translational repression, the members of the GW182 family, also participate in the deadenylation and decay of miRNA by interacting with argonaute proteins.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3G11, monoclonal
形式 buffered aqueous solution
分子量 antigen ~36.89 kDa
species reactivity human
technique(s) immunofluorescence: suitable
indirect ELISA: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NM_018996
UniProt登记号 Q9HCJ0
运输 dry ice
储存温度 ?20℃
Gene Information human ... TNRC6C(57690)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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