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Monoclonal Anti-SET07 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1300134
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Monoclonal Anti-SET07 antibody produced in mouse
Anti-PR/SET07
PR/SET domain-containing protein 07
Anti-Histone H4-K20 methyltransferase
Anti-H4-K20-HMTase
SET domain-containing protein 8
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.

免疫原

SET07 (AAF97812, N Terminal)
This antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SET07.

外形

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 43AT890, monoclonal
形式 buffered aqueous solution
species reactivity mouse, human
technique(s) indirect ELISA: 1:1000
western blot: 1:100-1:500
同位素/亚型 IgG1
NCBI登记号 AAF97812
UniProt登记号 Q9NQR1
运输 dry ice
储存温度 ?20℃
Gene Information human ... SET07(387893)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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