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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse

Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1404926
规格纯度
clone 2B10, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse
Nav1.9
NAN
SNS-2
SCN12A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM

免疫原

SCN11A (NP_054858, 1726 a.a. ~ 1791 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
TTTKRKEEERGAAIIQKAFRKYMMKVTKGDQGDQNDLENGPHSPLQTLCNGDLSSFGVAKGKVHCD

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2B10, monoclonal
形式 buffered aqueous solution
分子量 antigen ~33.37 kDa
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2aκ
NCBI登记号 NM_014139
UniProt登记号 Q9UI33
运输 dry ice
储存温度 ?20℃
Gene Information human ... SCN11A(11280)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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