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位置:首页 > 品牌 > Sigma-Aldrich > Monoclonal Anti-PIK3C2A, (C-terminal) antibody produced in mouse

Monoclonal Anti-PIK3C2A, (C-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402311
规格纯度
clone 3E7, purified immunoglobulin, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
Monoclonal Anti-PIK3C2A, (C-terminal) antibody produced in mouse
MGC142218
PI3-K-C2A
PI3-K-C2(ALPHA)
DKFZp686L193
CPK
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. (provided by RefSeq)

免疫原

PIK3C2A (NP_002636, 1577 a.a. ~ 1686 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLTAATYL

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

半岛bd体育手机客户端 性质

生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆3E7, monoclonal
形式buffered aqueous solution
分子量antigen ~38.21 kDa
species reactivityhuman
technique(s)immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG1κ
NCBI登记号NM_002645
UniProt登记号O00443
运输dry ice
储存温度−20℃
Gene Informationhuman ... PIK3C2A(5286)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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