半岛bd体育手机客户端 说明
一般描述
Leucine rich repeat kinase 2 (LRRK2) is a large protein containing protein-protein interaction region enclosing two main domains for : central kinase and GTPase.
免疫原
Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. <30% identity with LRRK1.
生化/生理作用
Mutation in the leucine rich repeat kinase 2 (LRRK2) gene causes familial Parkinson′s disease (PD) and sporadic PD. Mitochondrial dysfunction is observed as a result of LRRK2 gene variation.
特点和优势
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外形
PBS pH 7.4, 50% glycerol, 0.1% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | biotin conjugate |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | S231B-34, monoclonal |
形式 | buffered aqueous solution |
分子量 | antigen predicted mol wt 200 kDa |
species reactivity | human, rat |
浓度 | 1 mg/mL |
technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG2a |
NCBI登记号 | NP_940980 |
UniProt登记号 | Q5S007 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... LRRK2(120892) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich