Monoclonal Anti-LIG3 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

免疫原

Recombinant full-length human DNA Ligase III-b.

应用

Suggested starting dilutions are as follows: Blocking: Assay-dependent dilution, ICC/IF: Assay-dependent dilution, IP: Assay-dependent dilution, WB: Assay-dependent dilution, PLA: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

特点和优势

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外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	1F3, monoclonal
形式	liquid
分子量	100 kDa
species reactivity	mouse, chicken, human
浓度	1 mg/mL
technique(s)	immunocytochemistry: suitable immunofluorescence: suitable immunoprecipitation (IP): suitable proximity ligation assay: suitable western blot: suitable
同位素/亚型	IgG1
UniProt登记号	P49916
运输	wet ice
储存温度	?20℃
Gene Information	human ... LIG3(3980)

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable