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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-IRF4, (C-terminal) antibody produced in mouse

Monoclonal Anti-IRF4, (C-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403990
规格纯度
clone 2D1, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-IRF4, (C-terminal) antibody produced in mouse
LSIRF
MUM1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Interferon regulatory factor 4 (IRF4), also known as multiple myeloma oncogene-1 (MUM1), is a transcription factor. It is encoded by the gene mapped to human chromosome 6p25.3. The protein is specifically expressed in lymphocytes.

免疫原

IRF4 (NP_002451, 342 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LCNDRPNKLERDQTCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE

生化/生理作用

Interferon regulatory factor 4 (IRF4) plays a vital role in regulation of immunoglobulin class switch recombination and plasma cell differentiation. In addition, it is also implicated in maintaining homeostasis of both mature B and mature T lymphocytes. Mutation in the gene is associated with the risk of developing chronic lymphocytic leukemia (CLL).

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2D1, monoclonal
形式 buffered aqueous solution
分子量 antigen ~38.21 kDa
species reactivity human
technique(s) capture ELISA: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2bκ
NCBI登记号 NM_002460
UniProt登记号 Q15306
运输 dry ice
储存温度 ?20℃
Gene Information human ... IRF4(3662)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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