Monoclonal Anti-IL-33 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Interleukin 33 (IL-33) is a potent immunomodulatory cytokine that belongs to the IL-1 family. It is highly expressed in endothelial venules, endothelial cells and epithelium. The gene encoding this protein is localized on human chromosome 9p24.1.

免疫原

Mouse monoclonal IL-33 antibody was raised against the recombinant IL-33 protein.

生化/生理作用

Interleukin 33 (IL-33) functions as an extracellular cytokine and also translocates to the nucleus where it inhibits gene expression. IL-33 enhances the secretion of inflammatory cytokines and is associated with T-helper 2-type immune responses. It has been linked to chronic inflammatory diseases. High levels of IL-33 have been observed in the serum of patients with hepatocellular carcinoma and gastric cancer. Polymorphisms in this gene as well as its receptor are linked with atopic dermatitis, allergies and asthma.

特点和优势

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外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	12H6D12, monoclonal
形式	buffered aqueous solution
species reactivity	human, mouse
technique(s)	immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable
NCBI登记号	NP_254274
UniProt登记号	O95760
运输	dry ice
储存温度	?20℃
Gene Information	human ... IL33(90865)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable