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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-GTF2E2 antibody produced in mouse

Monoclonal Anti-GTF2E2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403893
规格纯度
clone 2C3, ascites fluid
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-GTF2E2 antibody produced in mouse
TF2E2
TFIIE-B
Fe
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Mouse monoclonal antibody raised against a full-length recombinant GTF2E2.
The gene GTF2E2 (general transcription factor IIE subunit 2) is mapped to human chromosome 8p12. The protein has a serine-rich region, a centrally located forkhead domain, a leucine repeat motif, a region similar to the bacterial σ factor subdomain 3, a bHLH (basic region-helix-loop-helix) motif and a bHL (basic region-helix-loop) sequence.

免疫原

GTF2E2 (AAH30572, 1 a.a. ~ 291 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSSKKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLDEILDETQHLDIGLKQKQWLMTEALVNNPKIEVIDGKYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKALGDQILFVNRPDKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKTHNEHLAGVLKDYSDITSSK

生化/生理作用

The gene GTF2E2 (general transcription factor IIE subunit 2) encodes the β subunit of transcription factor IIE (TFIIEβ). It has DNA binding ability and is essential for transcription. GTF2E2 also binds to RNA polymerase II. In patients with trichothiodystrophy, mutation in GTF2E2 is responsible for destabilization of TFIIE.

外形

Clear solution

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 ascites fluid
antibody product type primary antibodies
克隆 2C3, monoclonal
分子量 antigen ~58.12 kDa
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1:500-1:1000
同位素/亚型 IgG1κ
NCBI登记号 BC030572
UniProt登记号 P29084
运输 dry ice
储存温度 ?20℃
Gene Information human ... GTF2E2(2961)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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