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Monoclonal Anti-GATM, (N-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402784
规格纯度
clone 2H7, ascites fluid
价格
4618.16 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-GATM, (N-terminal) antibody produced in mouse
AGAT
AT
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. (provided by RefSeq)

免疫原

GATM (NP_001473.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTY

生化/生理作用

Glycine amidinotransferase (GATM) is involved in the formation of ornithine and guanidinoacetate from arginine and glycine. This is an important step in creatine synthesis. Mutations in the gene encoding GATM have been shown to lead to arginine-glycine amidinotransferase deficiency.

外形

Clear solution

基本信息

NACRESNA.41

半岛bd体育手机客户端 性质

生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆2H7, monoclonal
分子量antigen ~37.11 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgMκ
NCBI登记号NM_001482
UniProt登记号P50440
运输dry ice
储存温度−20℃
Gene Informationhuman ... GATM(2628)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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