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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-EWSR1 antibody produced in mouse

Monoclonal Anti-EWSR1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403797
规格纯度
clone 3A9, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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半岛bd体育手机客户端 名称:
Monoclonal Anti-EWSR1 antibody produced in mouse
EWS
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. (provided by RefSeq)

免疫原

EWSR1 (NP_005234, 358 a.a. ~ 453 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3A9, monoclonal
形式 buffered aqueous solution
分子量 antigen ~36.67 kDa
species reactivity human
technique(s) capture ELISA: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG1κ
NCBI登记号 NM_005243
UniProt登记号 Q01844
运输 dry ice
储存温度 ?20℃
Gene Information human ... EWSR1(2130)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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