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Monoclonal Anti-ENC1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1404588
规格纯度
clone 3C10, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-ENC1 antibody produced in mouse
CCL28
TP53I10
NRPB
FLJ39259
KLHL37
PIG10
KLHL35
ENC-1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) [PubMed 9305847] used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) [PubMed 9305847] termed these genes ′p53-induced genes,′ or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.[supplied by OMIM

免疫原

ENC1 (NP_003624, 17 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVL

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3C10, monoclonal
形式 buffered aqueous solution
分子量 antigen ~35.13 kDa
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG1κ
NCBI登记号 NM_003633
UniProt登记号 O14682
运输 dry ice
储存温度 ?20℃
Gene Information human ... ENC1(8507)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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