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Monoclonal Anti-CD82 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB4700755
规格纯度
clone C33, purified immunoglobulin, buffered aqueous solution
价格
3548.32 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Monoclonal Anti-CD82 antibody produced in mouse
4F9
R2
C33
IA4
Anti-KAI1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The cluster of differentiation 82 (CD82)/Kangai 1 (KAI1), a type III transmembrane protein, is a member of the tetraspanin superfamily. It has four putative transmembrane domains and one small and one large extracellular loop. CD82 is widely expressed in normal tissues. Its mRNA is seen at high levels in the spleen, placenta, lung, liver, kidney, and prostate. CD82 was previously identified as lymphocyte cell-surface protein. The KAI1/CD82 gene is mapped to human chromosome 11p11.2.

免疫原

C91/PL (human HTLV-1+ T cell line)

生化/生理作用

The cluster of differentiation 82 (CD82)/Kangai 1 (KAI1) protein is a metastasis suppressor. It inhibits the migration and invasion of cancer cells. CD82 plays a key role in cell adhesion, fusion, apoptosis, and morphogenesis. CD82 can mobilize intracellular Ca2+in lymphocytes. It acts as an accessory molecule in the activation of the T-cell. CD82 has an inhibitory role in syncytium formation caused by the human T-cell leukemia virus in immune cells (HTLV). Lower expression of CD82 is observed in several cancers, including prostate and lung cancer.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 C33, monoclonal
形式 buffered aqueous solution
species reactivity human
浓度 1 mg/mL
technique(s) FUNC: suitable
flow cytometry: suitable
immunoblotting: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同位素/亚型 IgG2a
NCBI登记号 NM_001024844.1
UniProt登记号 P27701
运输 wet ice
储存温度 2-8℃
Gene Information human ... CD82(3732)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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