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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-CBFA2T2 antibody produced in mouse

Monoclonal Anti-CBFA2T2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1404679
规格纯度
clone 2C10, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-CBFA2T2 antibody produced in mouse
DKFZp313F2116
MTGR1
EHT
ZMYND3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5′-region of the RUNX1 (AML1) gene fused to the 3′-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. (provided by RefSeq)

免疫原

CBFA2T2 (NP_001028171.1, 201 a.a. ~ 304 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LLLNTSIASPADSSELLMEVHGNGKRPSPERREENSFDRDTIAPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPNKMLE

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2C10, monoclonal
形式 buffered aqueous solution
分子量 antigen ~37.55 kDa
species reactivity human
technique(s) capture ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2bκ
NCBI登记号 NM_001032999
UniProt登记号 O43439
运输 dry ice
储存温度 ?20℃
Gene Information human ... CBFA2T2(9139)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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