半岛bd体育手机客户端 说明
应用
ML239 has been used as a proble in cellular lipid profiling.
包装
5, 25 mg in glass bottle
生化/生理作用
ML239 decreases the saturated and monounsaturated lysophosphatidylethanolamines in lung cancer cells and is toxic to breast cancer cells. ML239 may elicit toxicity by modulating the nuclear factor?κB (NF-κB) associated pathways.
ML239 is an inhibitor of breast cancer stem cells found from a screen using stem cell-like human mammary epithelial cells (HMLE). ML239 inhibited cancer stem cells with an IC50of 1.16 μM with 24-fold selectivity against the control cell line.
基本信息
| 经验(实验)分子式 | C13H10Cl3N3O2 |
| 分子量 | 346.60 |
| MDL编号 | MFCD23098913 |
| PubChem化学物质编号 | 329824724 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 15 mg/mL (clear solution) |
| 储存温度 | 2-8℃ |
| SMILES string | Clc1cc(Cl)c(OCC(=O)N\N=C\c2ccc[nH]2)c(Cl)c1 |
| InChI | 1S/C13H10Cl3N3O2/c14-8-4-10(15)13(11(16)5-8)21-7-12(20)19-18-6-9-2-1-3-17-9/h1-6,17H,7H2,(H,19,20)/b18-6+ |
| InChI key | NVEDPFICKAIHKD-NGYBGAFCSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 + H312 + H332 - H315 - H319 - H335 - H400 |
| 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
