您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

品牌
Sigma-Aldrich
货号
FCMAB186F
规格纯度
clone B-Ly1, Milli-Mark?, from mouse
价格
4681.07 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1
Membrane-spanning 4-domains subfamily A member 1

B-lymphocyte surface antigen B1

Leukocyte surface antigen Leu-16

Bp35

CD_antigen=CD20
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B cells, but is lost following differentiation into plasma cells (Tedder, 1994). In resting B cells, CD20 appears in a 33 kDa non-phosphorylated form. After mitogen stimulation, CD20 becomes heavily phosphorylated (35-37 kDa isoforms), and it is a dominant phosphoprotein in activated B cells and B-cell lines (Zhou, 1995). The long N- and C-terminal ends of the protein are located on the cytoplasmic side of the membrane and only a minor portion of the protein is exposed on the cell surface (Tedder, 1994). Antibodies reacting with CD20 cytoplasmic epitopes are designated CD20cy (Zhou, 1995). It is suggested that CD20 plays a direct role in regulating the transmembrane conductive Ca 2+ flux of B cells which indicates a possible function for CD20 as a regulator of proliferation and differentiation (Tedder, 1994).

特异性

Antibody recognizes Human CD20 antigen.

应用

This Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1 is validated for use in FC for the detection of CD20.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

质量

Evaluated by flow cytometry using human lymphocytes.

目标描述

33 kDa (Zhou, 1995)

外形

Protein A purified
Purified Mouse monoclonal IgG1k conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2

储存及稳定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析说明

Control
Human Lymphocytes

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.44

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 FITC conjugate
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 B-Ly1, monoclonal
species reactivity human
manufacturer/tradename Milli-Mark?
technique(s) flow cytometry: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_690605.1
UniProt登记号 P11836
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map