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位置: 首页> 品牌> Sigma-Aldrich> MBX-102

MBX-102

品牌
Sigma-Aldrich
CAS
24136-23-0
货号
SML0064
包装型号
规格纯度
≥98% (HPLC)
价格
1956.53 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
24136-23-0
MBX-102
JNJ39659100
(aR)-4-Chloro-a-[3-(trifluoromethyl)phenoxy]benzeneacetic acid 2-(acetylamino)ethyl ester
Arhalofenate
MBX-102/JNJ39659100
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

MBX-102 may be used in PPAR-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

MBX-102 has a potent transrepression effect on PPARγ. It is an oral glucose-reducing agent and also has insulin-sensitizing properties. It is useful as treatment for type 2 diabetes. MBX-102 also lowers triglycerides in a PPARα-independent manner.
MBX-102 is a selective PPAR modulator (SPPARM) and has been shown to inhibit phosphorylation of PPARγ. MBX-102 is converted to the active form, MBX-102 acid,in vivo.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式 C19H17ClF3NO4
分子量 415.79
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 white to tan
溶解性 DMSO: ≥35 mg/mL
创始人 Johnson & Johnson
储存温度 2-8℃

安全信息

象形图 GHS06GHS09
警示用语: Danger
危险声明 H301 - H319 - H400
预防措施声明 P273 - P301 + P310 + P330 - P305 + P351 + P338
危险分类 Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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