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LATS2 (480-1088), GST tagged human

品牌
Sigma-Aldrich
货号
SRP5202
规格纯度
recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4311.28 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
LATS2 (480-1088), GST tagged human
KPM
FLJ13161
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The kinase activity and two conserved domains within LATS2 are responsible for the suppression of tumorigenicity and inhibition of cell growth. LATS2 negatively regulates the cell cycle by controlling G1/S and/or G2/M transition. LATS2 interacts with the centrosomal proteins AURORA A and Ajuba and is required for accumulation of γ-tubulin and spindle formation at the onset of mitosis. LATS2 also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. LATS2 can also function as a co-repressor of androgen-responsive gene expression.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

重组 expressed in baculovirus infectedSf9 cells
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
分子量 ~98 kDa
NCBI登记号 NM_014572
运输 dry ice
储存温度 ?70℃
Gene Information human ... LATS2(26524)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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