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KAT5 (TIP60), Active

品牌
Sigma-Aldrich
货号
SRP0706
包装型号
规格纯度
recombinant
价格
6051.88 *本价格含增值税费
促销
服务
  • 原厂保证
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
KAT5 (TIP60), Active
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Useful for acetyltransferase assay.

生化/生理作用

Full-length recombinant human KAT5 was expressed byBaculovirusin Sf9 insect cells using an N-terminal GST tag. KAT5 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). KAT5 was originally isolated as an HIV-1 TAT-interactive protein that plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins(1). KAT5 protein is a histone acetylase that is involved in DNA repair and apoptosis and plays an important role in signal transduction. KAT5 acts as a cofactor of TAT that is involved in the regulation of HIV gene expression. KAT5 is also a co-regulator of transcription factors that either promote or suppress tumorigenesis(2).

重悬

Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

储存及稳定性

Store in aliquots at -70℃. Avoid freeze/thaw cycles.

半岛bd体育手机客户端 性质

重组 expressed in baculovirus infectedSf9 cells
测定 70-95% (SDS-PAGE)
形式 frozen liquid
specific activity 25-35 nmol/min·mg (radiometric)
分子量 ~88 kDa
浓度 0.1 μg/μL
登记号 NM_006388
运输 dry ice
储存温度 ?70℃
Gene Information human ... KAT5(10524)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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