JTE-607 - 半岛电竞官方网址

JTE-607

品牌

Sigma-Aldrich

CAS

188791-09-5

货号

SML2833

包装型号

规格纯度

≥98% (HPLC)

价格

1156.54 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

188791-09-5
JTE-607
(-)-Ethyl-N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl}-L-phenylalaninate dihydrochloride
JTE 607
N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

生化/生理作用

JTE-607 is a pro-drug, which carboxylic form (JTE-607-COOH) is a potent cytokine release inhibitor. JTE-607 reduces the production of proinflammatory cytokines in models of acute injury, septic shock and endotoxemia. It also inhibits proliferation of AML cellin vitroand in xenograft model. JTE-607 is an inhibitor of CPSF3 (pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3) that directly binds to CPSF3 and blocks the release of newly synthesized pre-mRNAs.

基本信息

经验(实验)分子式	C₂₅H₃₁Cl₂N₃O₅·2HCl
分子量	597.36
MDL编号	MFCD07363998

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable