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位置: 首页> 品牌> Sigma-Aldrich> N-[2-[(2-Methoxyphenyl)amino]-4′-methyl[4,5′-bithiazol]-2′-yl]acetamide

JNJ0966

N-[2-[(2-Methoxyphenyl)amino]-4′-methyl[4,5′-bithiazol]-2′-yl]acetamide

品牌
Sigma-Aldrich
CAS
315705-75-0
货号
SML2588
规格纯度
≥98% (HPLC)
价格
1057.08 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
315705-75-0
JNJ0966
N-[2-[(2-Methoxyphenyl)amino]-4′-methyl[4,5′-bithiazol]-2′-yl]acetamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

JNJ0966 is a potent and highly selective inhibitor of matrix metalloproteinase-9 (MMP-9) zymogen activation. It appears that JNJ0966 binds to a structural pocket in proximity to the MMP-9 zymogen cleavage site near Arg-106. JNJ0966 reduces disease severity in in a mouse experimental autoimmune encephalomyelitis (EAE) model. JNJ0966 does not inhibit activation of MMP-2 zymogen, and has no effect on MMP-1, MMP-2, MMP-3, MMP-9 or MMP-14 catalytic activity.

基本信息

经验(实验)分子式 C16H16N4O2S2
分子量 360.45
MDL编号 MFCD02045222

半岛bd体育手机客户端 性质

测定 ≥98% (HPLC)
形式 powder
颜色 white to beige
溶解性 DMSO: 2 mg/mL, clear
储存温度 2-8℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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