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IL13RA1/CD213A1 human

品牌
Sigma-Aldrich
货号
SRP6438
规格纯度
recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE)
价格
3896.85 *本价格含增值税费
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半岛bd体育手机客户端 名称:
IL13RA1/CD213A1 human
IL13Rα1
IL-13Ra
NR4
RP13-128O4.2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Interleukin 13 receptor, α 1, also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor α, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in HEK 293 cells
标签 6-His tagged (C-terminus)
测定 ≥98% (SDS-PAGE)
形式 lyophilized
分子量 calculated mol wt 38 kDa
observed mol wt 55-65 kDa by SDS-PAGE (DTT-reduced. Protein migrates due to glycosylation.)
包装 pkg of 10 and 50 μg
UniProt登记号 P78552
运输 wet ice
储存温度 ?20℃
Gene Information human ... IL13RA1(3597)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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