半岛bd体育手机客户端 说明
一般描述
IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
外形
Lyophilized from PBS and 0.5% trehalose.
重悬
Reconstitute with 100 μL deionized water.
其他说明
IL-36gamma (mouse) (aa 13-164) is untagged.
基本信息
NACRES | NA.32 |
半岛bd体育手机客户端 性质
生物来源 | mouse |
重组 | expressed inE. coli |
偶联物 | untagged |
测定 | >95% (SDS-PAGE) |
形式 | lyophilized |
分子量 | ~17 kDa |
包装 | pkg of 10 μg |
杂质 | <0.01 EU/μg endotoxin, tested |
颜色 | white |
UniProt登记号 | Q8R460 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | mouse ... Il36g(215257) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich