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IL-19 from mouse

品牌
Sigma-Aldrich
CAS
465617-97-4
货号
SRP6017
规格纯度
recombinant, expressed inE. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
价格
4148.84 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
465617-97-4
IL-19 from mouse
MDA1
IL-10C
ZMDA1
Melanoma differentiation association like protein
NG.1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

IL19 (interleukin 19) belongs to the IL-10 family of cytokines, and shares high homology with IL-20 and IL-24 at the primary level. It is further subcategorized into a subfamily containing IL-19, IL-20, and IL-24. It was first discovered in 2001, and its expression is not only limited to leukocytes and is also expressed by angiogenic tissue.

生化/生理作用

IL19 (interleukin 19) promotes the production of pro-inflammatory cytokines, such as IL-6 and TNF-α, and therefore, participates in the pathogenesis of autoimmune diseases such as psoriasis, asthma, and rheumatoid arthritis. This protein functions as a strong pro-angiogenic influence on different human EC (endothelial cell) types, such as umbilical vein, coronary artery, and microvascular types. In Th2 (T helper)-mediated colitis rat model IL-19 functions as an anti-inflammatory agent, and might have potential as a therapeutic target for alleviating colonic inflammation.

外形

Sterile filtered and lyophilized with no additives

重悬

Centrifuge the vial prior to opening. Reconstitute in H?O to a concentration of 0.1-0.5 mg/ml. The solution can be diluted into other aqueous buffers

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 mouse
重组 expressed inE. coli
测定 ≥95% (HPLC)
≥95% (SDS-PAGE)
形式 lyophilized
分子量 17.7 kDa
包装 pkg of 10 μg
杂质 Endotoxin, tested
NCBI登记号 Q8CJ70
UniProt登记号 Q8CJ70
运输 wet ice
储存温度 ?20℃
Gene Information mouse ... IL19(329244)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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