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IKK-γ, GST tagged human

品牌
Sigma-Aldrich
CAS
408328-74-5
货号
SRP5349
规格纯度
recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4432.73 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
408328-74-5
IKK-γ, GST tagged human
IP1
NEMO
IP2
AMCBX1
FIP-3
IP
IKK-gamma
Fip3p
FIP3
IPD2
IKBKG
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

IKKgamma is a serine/threonine protein kinase that phosphorylates the I-kappa-B protein which is an inhibitor of the transcription factor NF-kappa-B complex. Phosphorylation of I-kappa-B protein triggers the degradation of the inhibitor via the ubiquitination pathway, thereby activating NF-kappa-B complex. IKKgamma forms dimers and trimers and interacts preferentially with IKKbeta but not IKKalpha. IKKgamma associates with activated ATM after the induction of DNA double-strand breaks. ATM phosphorylates serine-85 of IKKgamma to promote its ubiquitin-dependent nuclear export.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in baculovirus infectedSf9 cells
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
分子量 ~73 kDa
NCBI登记号 NM_003639
application(s) cell analysis
运输 dry ice
储存温度 ?70℃
Gene Information human ... IKBKG(8517)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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