IFNA4

半岛bd体育手机客户端 说明

生化/生理作用

Recombinant Human IFNA4 was expressed inE. colicells. All known subtypes of IFN- alpha show the same antiviral antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. IFN-alpha and IFN-beta are thought to bind to the same receptor. Signal transduction mechanisms elicited after binding of IFN-alpha to its receptors involves tyrosine phosphorylation (see also: PTK; protein tyrosine kinase) of various non-receptor tyrosine kinases belonging to the Janus kinases.

重悬

Formulated as a lyophilized protein from a 0.2 um filtered solution in Tris and NaCl, pH 8.0. Upon reconstitution, working aliquots can be stored at 2-8℃ for one month, or at -20℃ for six months, with a carrier protein without detectable loss of activity.

储存及稳定性

The lyophilized protein is stable for at least one year from date of receipt at -70℃. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8℃ for one month, or at -20℃ for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

半岛bd体育手机客户端 性质

重组	expressed inE. coli
测定	70-95% (SDS-PAGE)
形式	lyophilized powder
分子量	~19.6 kDa
登记号	P05014
运输	dry ice
储存温度	?70℃
Gene Information	human ... IFNA4(3441)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable