半岛bd体育手机客户端 说明

一般描述

This ELISA antibody pair detects Human FGF-23
The FGF23 (fibroblast growth factor 23) gene is mapped to human chromosome 12p13.32 and encodes a phosphaturic hormone secreted by osteocytes. FGF23 is a 30 kDa protein and is part of the FGF19 subfamily.

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

The protein fibroblast growth factor 23 (FGF23) mainly controls phosphate homeostasis and induces its excretion. Fgf23 maintains normal serum phosphate and calcium levels, by suppressing the action of sodium phosphate co-transporters and 25-hydroxyvitamin D 1-α-hydroxylase. Deficiency of the encoded protein causes chronic kidney disease. Leptin, a protein highly expressed in obesity is known influence the expression of this protein. Thus, higher FGF23 gene expression is observed in obese individuals. The FGF23 gene affects cardiac properties and is associated with cardiovascular risk factors such as alcoholism.

其他说明

A sample Certificate of Analysis is available for this product. Please type the wordsamplein the text box provided for lot number.

基本信息

NACRES

NA.32

半岛bd体育手机客户端 性质

species reactivity	human
包装	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable
input	sample type cell culture supernatant(s) sample type plasma sample type serum sample(s)
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.3 ng/ml
detection method	colorimetric
运输	wet ice
储存温度	?20℃
Gene Information	human ... FGF23(8074)

安全信息

象形图
警示用语：	Warning
危险声明	H290
预防措施声明	P234 - P390
危险分类	Met. Corr. 1
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable