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HSP70, GST tagged human

品牌
Sigma-Aldrich
CAS
2071612-66-1
货号
SRP5255
规格纯度
recombinant, expressed inE. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4588.16 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
2071612-66-1
HSP70, GST tagged human
HSPA1A
HSPA1
HSP70-1
HSP72
HSPA1B. DAQB-147D11.1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

HSP70 is a member of the heat shock protein family and is synthesized by cells of many organisms in response to stress. HSP70 is found mostly but not exclusively in the nucleus of unstressed cells. For several hours after a short heat shock, however, it is strongly concentrated in nucleoli. Nucleoli are transiently damaged by such a heat shock: their morphology changes and assembly and export of ribosomes is blocked for several hours. HSP70 helps to stabilize the morphological changes of the nucleoli.
HSP70 (heat shock 70kDa)/Hsp70A1A (heat shock 70kDa protein 1A) is also termed as HSP72. It belongs to the molecular chaperones family. This gene is located on human chromosome 6p21.

生化/生理作用

HSP70 (heat shock 70kDa)/Hsp70A1A (heat shock 70kDa protein 1A) participates in several cellular processes, such as thermotolerance, clearance of protein aggregate, survival and proliferation. Mutation in Hsp70 gene locus is linked with systemic lupus erythematosus. Overexpression of this protein is observed in valproic acid (VPA)-resistant cell lines.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
分子量 ~96 kDa
NCBI登记号 NM_005345
application(s) cell analysis
运输 dry ice
储存温度 ?70℃
Gene Information human ... HSPA1A(3303)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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