半岛bd体育手机客户端 说明
生化/生理作用
STIP1 (stress induced phosphoprotein 1) is an adaptor protein, which helps HSP70 (heat shock protein) and HSP90 in protein folding. It interacts with HSP90 and substrate-bound HSP70 and thereby, helps in transferring of proteins from HSP70 to HSP90. It also induces ATPase activity of HSP70 and suppresses that of HSP90. STIP1 serves as a potential biomarker for ovarian carcinoma. In psoriatic epidermis, it might be associated with hyperproliferation and abnormal differentiation via ERK (extracellular signal-regulated kinase) and c-Jun N-terminal kinase (JNK).
外形
4.5 mg/ml in 40 mM Hepes, pH 7.5.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
| NACRES | NA.32 |
半岛bd体育手机客户端 性质
| 生物来源 | human |
| 重组 | expressed inE. coli |
| 测定 | ≥99% (SDS-PAGE) |
| 形式 | liquid |
| 包装 | pkg of 25 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <1 EU/μg (LAL test) |
| NCBI登记号 | P31948 |
| 运输 | dry ice |
| 储存温度 | ?70℃ |
| Gene Information | human ... STIP1(10963) |
Sigma-Aldrich
m.cnreagent.com
