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Histone Octamer full length human

品牌
Sigma-Aldrich
货号
SRP0408
规格纯度
recombinant, expressed inE. coli, ≥90% (SDS-PAGE)
价格
9148.9 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Histone Octamer full length human
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Human recombinant histone octamer consisting of 2 molecules each of histones H2A (GenBank Accession No. NM_033445) amino acids 2-130(end) with a N-terminal His-tag, H2B (GenBank Accession No. NM_003528) amino acids 2-126(end) with a N-terminal His-tag, H3 (GenBank Accession No. NM_003532) amino acids 2-137(end) with a N-terminal His-tag, and H4 (GenBank Accession No. NM_003548) amino acids 2-103(end) with a N-terminal His-tag, expressed in anE. coliexpression system.

生化/生理作用

The nuclear DNA in eukaryotes is found to be associated with histones to form a compact complex called nucleosome. Histones neutralize the electrostatic nature of DNA and function as scaffolding proteins. Each core nucleosome contains two copies each of the core histones H2A, H2B, H3, and H4 to form an octameric complex. This octameric complex contains a central (H3-H4)2tetramer flanked on both sides with H2A-H2B dimers. The octamer complex function in various stages of chromosome function, chromatin assembly and nucleosome formation. The histone dimer-tetramer interactions are also important in RNA transcription.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥90% (SDS-PAGE)
形式 aqueous solution
分子量 113.8 kDa
包装 pkg of 100 μg
NCBI登记号 NM_003528
NM_003532
NM_003548
NM_033445
运输 dry ice
储存温度 ?70℃
Gene Information human ... HIST1H2BG(8339), HIST2H2AC(8338), HIST3H3(8290), HIST4H4(121504)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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