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HIPK2, active, GST tagged from mouse

品牌
Sigma-Aldrich
货号
SRP5313
规格纯度
PRECISIO?, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
5909.71 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
HIPK2, active, GST tagged from mouse
B230339E18Rik
Stank
1110014O20Rik
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors. HIPK2 enhances expression of p53 target genes that resulting in growth arrest and the enhancement of UV-induced apoptosis that could be inhibited by antisense to HIPK2. HIPK2 as a target for MDM2 mediated ubiquitin-dependent degradation that only occurred in growth-arresting conditions when MDM2 was efficiently induced by p53. The knockdown of HIPK2 using small interfering RNA reduced p53 binding and activation of p53R2 that resulting in impaired UV-induced DNA repair.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 mouse
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 88-132 nmol/min·mg
分子量 ~72 kDa
NCBI登记号 BC031904
application(s) cell analysis
运输 dry ice
储存温度 ?70℃
Gene Information mouse ... Hipk2(15258)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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