半岛bd体育手机客户端 说明
一般描述
HDAC5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. HDAC 5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis. HDAC5 can co-immunoprecipitates with HDAC3 family members forming multicomplex proteins. HDAC5 can also interact with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 gene is thought to be associated with colon cancer.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
制备说明
After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.
基本信息
NACRES | NA.32 |
半岛bd体育手机客户端 性质
生物来源 | mouse |
重组 | expressed in baculovirus infectedSf9 cells |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
specific activity | 88-154 RLU/min·ng |
分子量 | ~80 kDa |
NCBI登记号 | BC060609 |
application(s) | genomic analysis |
运输 | dry ice |
储存温度 | ?70℃ |
Gene Information | mouse ... Hdac5(15184) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |