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位置: 首页> 品牌> Sigma-Aldrich> Fosaprepitant dimeglumine

Fosaprepitant dimeglumine

品牌
Sigma-Aldrich
CAS
265121-04-8
货号
SML2228
规格纯度
≥98% (HPLC)
价格
858.16 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
265121-04-8
Fosaprepitant dimeglumine
[3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl] ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid
1-Deoxy-1(methylamino)-D-glucitol[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate (2:1) (salt)
L-758,298
MK-0517
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

Fosaprepitant dimeglumine acts as a therapeutic agent to treat chemotherapy-induced nausea and vomiting. It also acts as a weak inhibitor of cytochrome P450 3A4 (CYP3A4).
Fosaprepitant dimeglumine is a Substance P/neurokinin-1 (NK1) receptor antagonist. It is a water soluble prodrug of the antiemetic drug aprepitant.

基本信息

经验(实验)分子式 C23H22F7N4O6P · C14H34N2O10
分子量 1004.83
NACRES NA.77

半岛bd体育手机客户端 性质

测定 ≥98% (HPLC)
形式 powder
旋光性 [α]/D +27 to +34°, c = 0.5 in methanol
储存条件 desiccated
颜色 white to beige
溶解性 H2O: 2 mg/mL, clear
运输 wet ice
储存温度 ?20℃
SMILES string FC1=CC=C([C@@H]2N(CCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)CC(NC4=O)=NN4P(O)(O)=O)C=C1.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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