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EGF-L7 human

品牌
Sigma-Aldrich
货号
SRP3319
规格纯度
recombinant, expressed inE. coli, ≥98% (SDS-PAGE or HPLC), ≥98% (HPLC)
价格
4374.74 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
EGF-L7 human
Multiple EGF-like domains protein 7
MEGF7
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

EGF-L7 (Epidermal Growth Factor Like Protein 7, Multiple EGF Like Domains Protein 7, VE Statin) is a multi-domain protein containing two EGF like domains and one EMI domain. It is expressed almost exclusively in endothelial cells and functions to promote normal development of the vascular system, particularly tubulogenesis. EGF-L7 is capable of antagonistic binding to Notch receptors resulting in the inhibition of Notch signaling in HUVEC and neural stem cells. In research models inducing hypoxia and subsequent reoxygenation, (H/R), EGF-L7 can inhibit ICAM-1 expression and enhance the inhibition of NF-kappaB activation. Additionally, EGF-L7 can chemoattract endothelial cells and bind to the extracellular matrix. The overexpression of EGF-L7 is observed in various cancers, and is generally correlated with increased metastasis and a poor prognosis. Recombinant human EGF-L7 is a 28 kDa protein containing 251 amino acid residues.

生化/生理作用

EGF-L7 (Epidermal Growth Factor Like Protein 7, Multiple EGF Like Domains Protein 7, VE Statin) is a multi-domain protein containing two EGF like domains and one EMI domain. Recombinant human EGF-L7 is a 28 kDa protein containing 251 amino acid residues.

外形

Lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥98% (HPLC)
≥98% (SDS-PAGE or HPLC)
形式 lyophilized
分子量 28.0 kDa
包装 pkg of 10 μg
杂质 endotoxin, tested
UniProt登记号 Q9UHF1
运输 wet ice
储存温度 ?20℃
Gene Information human ... EGFL7(51162)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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