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CXADR/CAR human

品牌
Sigma-Aldrich
货号
SRP6446
规格纯度
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
价格
3563.77 *本价格含增值税费
促销
服务
  • 原厂保证
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  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
CXADR/CAR human
CAR4/6
HCAR
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Coxsackie virus and adenovirus receptor (CXADR) also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V type (D1) and a C2 type (D2) Iglike domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in HEK 293 cells
测定 ≥95% (SDS-PAGE)
形式 lyophilized
分子量 calculated mol wt 24.9 kDa
observed mol wt 35 kDa by SDS-PAGE (reducing) (Leu 20 is the predicted N-terminal .)
包装 pkg of 10 and 50 μg
杂质 <1 EU/μg endotoxin (LAL test)
UniProt登记号 P78310
运输 wet ice
储存温度 ?20℃
Gene Information human ... CXADR(1525)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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