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CK1 δ, active, GST tagged human

品牌
Sigma-Aldrich
货号
SRP5014
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6468.88 *本价格含增值税费
促销
服务
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数量
-+
半岛bd体育手机客户端 名称:
CK1 δ, active, GST tagged human
CSNK1D
HCKID
CK1D
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Casein kinase 1 δ (CK1δ) is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes, including DNA replication and repair.

生化/生理作用

CK1δ is a regulator of Yes-associated protein (YAP) transcription coactivator, which is a key regulator of organ size and a candidate human oncogene. CK1d is activated by CCK2R and it then phosphorylates polycystin 2 (PKD2) at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CKId can phosphorylate in vitro deoxycytidine kinase (dCK), which is a key enzyme in the salvage of deoxynucleosides. Phosphorylation of dCK by CKId in vitro correlates with increased activity of this enzyme.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

半岛bd体育手机客户端 性质

重组expressed in baculovirus infected Sf9 cells
半岛bd体育手机客户端 线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity70-94 nmol/min·mg
分子量 ~72 kDa
NCBI登记号NM_001893
运输dry ice
储存温度−70℃
Gene Informationhuman ... CSNK1D(1453)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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