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位置: 首页> 品牌> Sigma-Aldrich> Caged MK801

Caged MK801

品牌
Sigma-Aldrich
CAS
217176-91-5
货号
SML0304
包装型号
规格纯度
≥98% (HPLC)
价格
7551.95 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
217176-91-5
Caged MK801
Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate
10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
cMK801
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

10, 50 mg in glass bottle

生化/生理作用

Caged MK801 is an inactive caged form of the potent selective non-competitive irreversible NMDA glutamate receptor open-channel blocker MK801. Caged MK801 is cleaved by exposure to UV light, liberating the active MK801. The caged compound is stable within cells. Intracellular compartment-specific photorelease allowed study the locus of induction and expression of timing-dependent long-term depression (t-LTD). Caged MK801 is thus a useful tool to uncover compartment-specific biological functions.

特点和优势

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C26H24N2O6
分子量 460.48
PubChem化学物质编号 329825309
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 protect from light
颜色 white to light yellow
溶解性 DMSO: ≥10 mg/mL
储存温度 2-8℃
SMILES string COc1cc(COC(=O)N2[C@@H]3Cc4ccccc4[C@@]2(C)c5ccccc35)c(cc1OC)[N+]([O-])=O
InChI 1S/C26H24N2O6/c1-26-19-10-6-4-8-16(19)12-22(18-9-5-7-11-20(18)26)27(26)25(29)34-15-17-13-23(32-2)24(33-3)14-21(17)28(30)31/h4-11,13-14,22H,12,15H2,1-3H3/t22-,26+/m1/s1
InChI key WZDXUEMCALAOAY-GJZUVCINSA-N

Sigma-Aldrich

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