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BRPF3 (576-701) GST tag human

品牌
Sigma-Aldrich
货号
SRP6580
规格纯度
recombinant, expressed inE. coli, ≥95% (SDS-PAGE)
价格
3563.77 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
BRPF3 (576-701) GST tag human
Bromodomain and PHD Finger Containing 3
MGC:58603
KIAA1286
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. Bromodomain and PHD finger containing 3 (BRPF3) is a component of the MOZ/MORF histone acetyltransferase (HAT) complex. The addition of BRPF proteins to MOZ/MORF increases its HAT activity.3 Consequently, BRPF3 is likely to play a role in regulation of transcriptional activation by MOZ/MORF. This product contains the first bromodomain of BRPF3.

外形

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5 mM β-mercaptoethanol and 5% glycerol.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥95% (SDS-PAGE)
形式 liquid
分子量 41.2 kDa (576-701 aa + NT GST Tag)
包装 pkg of 100 μg
pkg of 20 μg
UniProt登记号 Q9ULD4
运输 dry ice
储存温度 ?70℃
Gene Information human ... BRPF3(27154)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317 - H319 - H412
预防措施声明 P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313
危险分类 Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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