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BRD1 (556-680) GST tag human

品牌
Sigma-Aldrich
货号
SRP6564
规格纯度
recombinant, expressed inE. coli, ≥95% (SDS-PAGE)
价格
3487.6 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
BRD1 (556-680) GST tag human
Bromodomain containing 1
DKFZp686F0325
BRPF2
BRPF1
Bromodomain and PHD finger-containing protein 2
BRL
BR140-like protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. BRD1 is a bromodomain containing protein that has been identified as a susceptibility gene in neurological disorders, such as schizophrenia and bipolar affective disorder. This protein can be used for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

外形

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥95% (SDS-PAGE)
形式 liquid
分子量 41.1 kDa (556-680 aa + NT GST Tag)
包装 pkg of 100 μg
pkg of 20 μg
UniProt登记号 O95696
运输 dry ice
储存温度 ?70℃
Gene Information human ... BRD1(23774)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317 - H319 - H412
预防措施声明 P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313
危险分类 Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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