Biotin-dPEG^?₁₂-TFP ester

半岛bd体育手机客户端 说明

特点和优势

Biotin-dPEG^?₁₂-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG^?₁₂-TFP ester has a long spacer of precise length (47.6 ?) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

基本信息

经验(实验)分子式	C43H69F4N3O16S
分子量	992.08
PubChem化学物质编号	329823872
NACRES	NA.22

半岛bd体育手机客户端 性质

测定	>90%
形式	solid or viscous liquid
reaction suitability	reaction type: Biotinylations reaction type: Biotinylations reactivity: amine reactive reagent type: cross-linking reagent
聚合物结构设计	shape: linear functionality: monofunctional
运输	ambient
储存温度	?20℃
SMILES string	O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)OC3=C(C(F)=CC(F)=C3F)F

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable