Bcl-2, C-Terminal Truncated, His·Tag^?, Human, Recombinant,E. coli

半岛bd体育手机客户端 说明

一般描述

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His?Tag sequence, and expressed inE. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.
Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His-Tag sequence and expressed inE. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.

包装

50 μg in Glass bottle
Please refer to vial label for lot-specific concentration.

应用

Neutralization (see biological activity)

生化/生理作用

EC?? = 100-300 nM based on its ability to inhibit 54 nM caspase-8-cleaved human Bid-mediated release of cytochrome c from isolated mouse liver mitochondria

警告

Toxicity: Standard Handling (A)

外形

In 100 mM KCl, 10 mM HEPES, 20% glycerol, pH 8.0.

重悬

Following initial thaw, aliquot and freeze (-20°C).

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
重组	expressed inE. coli
测定	≥95% (SDS-PAGE)
形式	liquid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze avoid repeated freeze/thaw cycles
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable