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BAX, GST tagged human

品牌
Sigma-Aldrich
CAS
480064-98-0
货号
SRP5166
规格纯度
recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6262.52 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
480064-98-0
BAX, GST tagged human
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

BCL2 associated X, apoptosis regulator (BAX) is a proapoptotic protein of the B-cell lymphoma 2 (BCL2) protein family. The gene encoding it is localized on human chromosome 19q13.33.

生化/生理作用

BCL2 associated X, apoptosis regulator (BAX) forms a heterodimer with B-cell lymphoma 2 (BCL2) and functions as an apoptotic activator. BAX interacts with and increases the opening of the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in the mitochondrial membrane potential and the release of cytochrome c. The expression of BAX gene is regulated by the tumor suppressor p53 and BAX has been shown to be involved in p53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRESNA.32

半岛bd体育手机客户端 性质

生物来源human
重组expressed in E. coli
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
分子量 ~49 kDa
NCBI登记号NM_004324
application(s)cell analysis
运输dry ice
储存温度−70℃
Gene Informationhuman ... BAX(581)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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