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ATG13, GST tagged human

品牌
Sigma-Aldrich
货号
SRP5341
规格纯度
recombinant, expressed inE. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
4432.73 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
ATG13, GST tagged human
KIAA0652
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

ATG13 is a protein that is part of the autophagy complex which is the major route by which cytoplasmic contents are delivered to the lysosome for degradation. ATG13 localizes on the autophagic isolation membrane and is essential for autophagosome formation. In mammals, ATG13 interacts with ATG1 (ULK1/2) and FIP200 to form the autophagy. ATG101 can also bind to ATG13 protein and is important for the stability and basal phosphorylation of ATG13 and ULK1. mTOR can suppress the autophagy process through direct regulation of the ULK1-Atg13-FIP200 complex where mTOR has been shown to phosphorylate ATG13.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

重组 expressed inE. coli
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
分子量 ~96 kDa
NCBI登记号 NM_001142673
运输 dry ice
储存温度 ?70℃
Gene Information human ... ATG13(9776)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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