Arimoclomol maleate

品牌

Sigma-Aldrich

CAS

289893-26-1

货号

SML3015

包装型号

规格纯度

≥98% (HPLC)

价格

841.96 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

289893-26-1
Arimoclomol maleate
BRX 220
maleate salt
N-[(2R)-2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidoyl chloride 1-oxide, maleate salt
(R)-3-(Chloro(2-hydroxy-3-(piperidin-1-yl)propoxyimino)methyl)pyridine 1-oxide, maleate salt
(+)-(R)-N-[2-Hydroxy-3-(1-piperidinyl)propoxy]pyridine-1-oxide-3-carboximidoyl chloride, maleate salt
BRX-220
Anti-neurodegeneration agent 1
BRX220

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

生化/生理作用

Arimoclomol is an orally available, CNS-penetrant coinducer of heat shock proteins (HSPs), notably HSP70, that exhibits in vivo efficay in disease models of diabetes, Gaucher disease (GD), sporadic inclusion body myositis (sIBM), and neurological disorders, including amyotrophic lateral sclerosis (ALS) and Niemann-Pick disease type C1 (NPC1). Note: arimoclomol maleate and citrate salt forms are known as BRX-220 and BRX-345, respectively.

基本信息

经验(实验)分子式	C₁₄H₂₀ClN₃O₃· C₄H₄O₄
分子量	429.85
MDL编号	MFCD28143527

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	Cl/C(C1=CC=C[N+]([O-])=C1)=N\OC[C@@H](CN2CCCCC2)O.O=C(O)/C=C\C(O)=O