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Anti-Zinc finger protein 593

品牌
Sigma-Aldrich
货号
ABE1358
规格纯度
from rabbit, purified by affinity chromatography
价格
4603.28 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Zinc finger protein 593
ZFP593, Zinc finger protein T86
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Zinc finger protein 593 (UniProt: O00488; also known as Zinc finger protein T86) is encoded by the ZNF593 (also known as ZT86) gene (Gene ID: 51042) in human. Zinc fingers are small protein domains wherein zinc plays a structural role contributing to the stability of the domain. Proteins containing zinc fingers are structurally diverse and perform a broad range of functions, including DNA replication and repair, transcription and translation, metabolism, cell proliferation, and apoptosis. Zinc finger domain 593 (ZNF593) belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family and contains a single C2H2 type zinc finger (amino acids 61-85). ZFP593 is largely disordered, with the exception of the zinc finger domain. It displays ubiquitous distribution and has been detected in spleen, prostate, testis, small intestine, and colon and in lower levels in thymus and peripheral blood leukocytes. ZFP593 is shown to negatively modulate the DNA binding activity of Oct-2. It can act either by binding to DNA octamer or by interacting with Oct-2. (Ref.: Srikrishna, S., et al. (2003), Nucleic Acid Res. 31(2): 532-550).

特异性

This polyclonal antibody detects zinc finger protein 593 in murine embryonic stem cells. It targets an epitope of 14 amino acids from the C-terminus.

免疫原

KLH-conjugated linear peptide corresponding to 14 amino acids from the C-terminal end of human Zinc finger protein 593.

应用

Research Category
Epigenetics & Nuclear Function
Anti-Zinc finger protein 593 Antibody, Cat. No. ABE1358, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein 593 and has been tested in Immunoprecipitation and Western Blotting.
Western Blotting Analysis: A 1:500 dilution from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).

Immunoprecipitation Analysis: 2 ug from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).

质量

Evaluated by Western Blotting in mouse embryonic stem cells.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Zinc finger protein 593 in 10 ?g of mouse embryonic stem cells lysate.

目标描述

~15 kDa observed. 15.20 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

外形

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity mouse
species reactivity (predicted by homology) rhesus macaque (based on 100% sequence homology), human (based on 100% sequence homology), bovine (based on 100% sequence homology)
technique(s) immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号 NP_056955
UniProt登记号 O00488
运输 ambient

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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