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Anti-XAF1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1407566
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
6644.93 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-XAF1 antibody produced in mouse
XIAPAF1
BIRC4BP
HSXIAPAF1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM

免疫原

XAF1 (NP_059993.2, 1 a.a. ~ 301 a.a) full-length human protein.

Sequence
MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKKHFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLDPLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~34.6 kDa
species reactivity human
technique(s) indirect immunofluorescence: suitable
western blot: 1 μg/mL
NCBI登记号 NM_017523.2
UniProt登记号 Q6GPH4
运输 dry ice
储存温度 ?20℃
Gene Information human ... XAF1(54739)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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