Anti-West Nile Virus Envelope antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

免疫原

West Nile virus Envelope antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of the West Nile virus envelope protein.The immunogen is located within amino acids 500 - 550 of West Nile Virus Envelope.

应用

WNV Env antibody can be used for the detection of the West Nile virus Envelope protein in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.

外形

Supplied in PBS containing 0.02% sodium azide.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	West Nile virus
浓度	1 mg/mL
technique(s)	ELISA: suitable
同位素/亚型	IgG
NCBI登记号	NP_776014
UniProt登记号	P06935
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable